Chymique : the alchemist never actually produces the elixir of life, but only some medicinal or smelling thing, which falls far short of his expectations.
Winter-seeming summer’s night : a contradictory thing. We have every justification for expecting that it will be good, but in practice it turns out rather different.
Mary : more likely to be an archaic form for ‘marrow’ than the ‘marry’ often substituted.
Spheares : the harmony of the spheres : the divine harmony of the universe in motion.
Mummy : an embalmed body, a body without a mind.